HIGHLIGHTED TOPIC Imaging Lung Physiology Role of glutathione in lung retention of Tc-hexamethylpropyleneamine oxime in two unique rat models of hyperoxic lung injury
نویسندگان
چکیده
Said H. Audi, David L. Roerig, Steven T. Haworth, and Anne V. Clough Departments of Biomedical Engineering and Mathematics, Statistics and Computer Science, Marquette University, Milwaukee, Wisconsin; Division of Pulmonary and Critical Care Medicine and Departments of Anesthesiology and Pharmacology/Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin; and Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin
منابع مشابه
Role of glutathione in lung retention of 99mTc-hexamethylpropyleneamine oxime in two unique rat models of hyperoxic lung injury.
Rat exposure to 60% oxygen (O(2)) for 7 days (hyper-60) or to >95% O(2) for 2 days followed by 24 h in room air (hyper-95R) confers susceptibility or tolerance, respectively, of the otherwise lethal effects of subsequent exposure to 100% O(2). The objective of this study was to determine if lung retention of the radiopharmaceutical agent technetium-labeled-hexamethylpropyleneamine oxime (HMPAO)...
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